Clinical Toxicology of Commercial Products, Acute Poisoning

HUGO DUNLAP SMITH
1969 Archives of Pediatrics & Adolescent Medicine  
238 years. Plutonium is not at present an ences are also included. Section V is an important contributor, though it will alphabetical listing of 17 000 commercial remain as the chief contaminant after products. Each entry details the manuthe fission products have decayed away. facturer, and the ingredients, with an In general the papers represent typical asterisk against ones likely to produce applications of the science of health major toxic effects. Section VI describes physics to what is
more » ... sics to what is recognised to be one of the usual constituents of substances of the major problems of nuclear energy. unknown generic origin, and Section VII The general reader will perhaps be com-gives the addresses and telephone numbers forted by Dr H. M. Parker's closing re-of American manufacturers. mark that acceptance of risk is 'a societal This book is obviously of the greatest problem and all that we (scientists) can do value for American medicine. The fact is to place our concepts of the real risk that the commercial index is derived from before the public, honestly and forth-compounds widely used in the United rightly, and hope (for) ... agreement on States reduces the value of Section V for these risks sometime before we get to the physicians on this side of the Atlantic. nuclear economy of the year 2000'. However, British physicians involved with industrial medicine, toxicology and M. DAY poisoning will find most of it appropriate Clinical Toxicology of Commercial Proand much of it useful. ducts: Acute Poisoning. . 3rd Edition. (Pp.356; $21l50.) Charles C. Thomas; Illinois. 1976. Anyone familiar with previous editions of this book will welcome the appearance of Poisoning is now a major cause of acute the fourth edition. Still under the same admissions to hospital, and an important management, this compendious reference cause of death. This book is a laboratory work should prove as popular as its pre-manual for the detection and quantificadecessors. tion of poisons, particularly drugs. The Like previous editions, the book is first part of the book is of a more general divided into seven sections and it is essen-nature dealing with emergency toxicology, tial for readers to understand how it is analyses of liver, alimentary tract, brain set out if they are to realise the full poten-and kidney, as well as abuse screening. tial of the work. In order to make this The second part is an alphabetical list of clearer, the authors have incorporated a poisons with methods for their deterflow chart opposite the fifth page which mination and information on the interpreguides the uninitiated through the tation of the results. (coloured) sections. The book contains some disappoint-Section I contains a brief and un-ments. The methods advocated rely remarkable account of the first aid and heavily on spectrophotometry, the specifiemergency treatment of acute poisoning. city and sensitivity of which are now very This is a gentle introduction to the detailed suspect. There is little mention of modern systematic account of supportive managemass spectrometric and mass fragmentoment in Section IV. Both are written graphic methods of identification and clearly, with the needs of practising analysis, radioimmunoassay, and polaroclinicians in mind. graphy. The volume will be of value to Sections II, III, V and VI are the real forensic scientists; its value to clinical meat. Section II gives alphabetical and biochemists will be less because of the innumerical indices (Chemical Abstract creasing realisation that analytical data Service Registry Number) to short have a very limited place in the manageaccounts of the toxicology of over 1300 ment of acute poisoning. Only for those substances, or classes of substances. Each drugs where specific methods of treatentry categorises the compound into one ment exist, can such laboratory data be of 80 'reference congeners' which are regarded as important. For the large fully described in Section III. Each majority, clinical management, irrespective reference congener typifies a group of re-of the quantitative findings, represents the lated compounds, stressing toxic signs only effective means of preserving life. and symptoms as well as appropriate programmes of treatment. Important refer-MICHAEL D. RAWLINS Book reviews. Occupiers' Liability Act 1957 and the. Liability of Hospitals. By B. Williams. (Pp. 69; £6 soft cover, £8 hard cover4
doi:10.1001/archpedi.1969.02100040543031 fatcat:dgi2q6gfb5g5xp5fc7s2nldc64