Case Report of Toxic Shock-Like Syndrome due to Group A Streptococcal Infection
A群溶血性連鎖球菌によるtoxic shock like syndromeの1例

Yoshikata SHIMIZU, Akihiro OHYMAMA, Kazunori KASAMA, Masumi MIYAZAKI, Kenji OOE, Yasumi OOKOCHI
1993 Kansenshogaku zasshi  
A case of streptococcal toxic shock like syndrome occurring in a 44-year-old previousluy healthy Japanese male is reported. He initially had a sore thoat, low grade fever, diarrhea and mild pains in a lower extremities. Shortly thereafter, he rapidly developed a high fever, profound hypotension, multifocal epidermal necrosis, and sever purulent fascitis and myositis in both lower etremities, which required above knee amputation of both legs. He later developed disseminated intravascular
more » ... travascular coagulapathy, adult respiratory distress syndrome, acute renal failure, coma and necrotizing inflamation of both arms and external genitalia despite treatment. He died on the 13th hospital day. Streptococcus pyogenes was isolated from the necrotic muscles and right knee joint. The organism was typed as M3, T3, was sensitive to penicillins, and was found to be producting streptococcal pyogenic exotoxin A in vitro. This is the first case report of streptococcal toxic shock like syndrome in Japan.
doi:10.11150/kansenshogakuzasshi1970.67.236 pmid:8486981 fatcat:nvnu2jt54zhkhahzul6mwiy5zq