Case Report Rosai-Dorfman disease (RDD) in the paraglottic space: report of a case and review of literature

Yu-Ling Ma, Zhuo-Ping Liang, Sheng-En Xu, Zhi-Hui Yang, Yi Peng, Xiao-Qiang Sun, Gang Qin
2015 Int J Clin Exp Pathol   unpublished
Sinus histiocytosis with massive lymphadenopathy is also known as Rosai-Dorfman disease (RDD) and is characterized by painless bilateral cervical lymphadenopathy. In the present case report, a 67-year-old Chinese woman presented with a 3-month history of progressive voice hoarseness, progressive dyspnea on exertion and a foreign body sensation. MRI revealed a lesion involving the right side of the paraglottic space. The lesion was totally resected. Based on the histologic features and
more » ... tivity for the S-100 protein and CD68, a diagnosis of RDD was made. We described an extremely unique case of RDD that was observed in the paraglottic space and discussed its clinical and histopathologic features, differential diagnoses and treatment options.