A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is
Results: In SLE patients respect to HC, plasma IL-1b levels were unmodified whereas IL-6 was higher, resulting significantly increased in SLE-S. Monocytes isolated from SLE patients released lower quantities of IL-1b after stimulation with BzATP, whereas the release of both IL-6 and TNF-a was significantly augmented in SLE-NS respect to both HC and SLE-S subjects after all types of stimulation. RT-PCR showed reduced P2X7R and augmented NLRP3 mRNA expression in SLE patients. Accordingly, P2X7Rdoi:10.1136/annrheumdis-2019-eular.3361 fatcat:kl7wylv4uffq7gnm2ztujlxmam