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Biobased Hyperbranched Poly(ester)s of Precise Structure for the Release of Therapeutics
2021
Medical Research Archives
Hyperbrached poly(ester)s derived from naturally-occurring biomonomers may serve as excellent platforms for the sustained-release of therapeutics. Those generated from glycerol are particularly attractive. Traditionally, the difference in reactivity of the hydroxyl groups of glycerol has precluded the formation of well-defined polymers at high monomer conversion without gelation. Using the Martin-Smith model to select appropriate monomer ratios (ratios of functional groups), polymerization may
doi:10.18103/mra.v9i1.2308
fatcat:iugy2ujdnveedlqv3oyrzvzcd4