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Expression of 17beta-hydroxysteroid dehydrogenase types 1, 2, 3 and 4 in the human temporal lobe
Journal of Endocrinology
Sex steroid hormones exert important biological effects on the brain. Moreover, an extensive sex steroid metabolism occurs in the brain. In sex steroid metabolism 17hydroxysteroid dehydrogenases (17 -HSDs) play essential roles in catalyzing the final steps in androgen and estrogen biosynthesis. Recently four types of human 17 -HSDs and a pseudogene of the type 1 isoform were identified. To date, 17 -HSD has not been extensively studied in the human brain. Therefore, we investigated the mRNAdoi:10.1677/joe.0.1600119 pmid:9854183 fatcat:uzaarzohdngkppld724g5v74b4