Adherence to antiretroviral therapy among people living with HIV and AIDS in Monze and Nyimba districts of Zambia

Emmanuel Mwila Musenge
2016 TEXILA INTERNATIONAL JOURNAL OF CLINICAL RESEARCH  
The control of human immunodeficiency virus and acquired immune deficiency syndrome depends on several factors which include life-long commitment to antiretroviral therapy. Poor adherence to antiretroviral therapy leads to serious consequences such as drug resistance and eventually high morbidity and mortality. We assessed adherence to antiretroviral therapy and associated factors among people living with human Immunodeficiency virus and acquired immune deficiency syndrome. Materials and
more » ... aterials and methods: This cross-sectional study was conducted in Monze and Nyimba districts of Zambia. A simple random sample of 364 consenting participants attending antiretroviral therapy clinic was selected between February and March 2015. A structured interview schedule was used to collect data. Multivariate binary logistic regression analysis was carried out using IBM ® SPSS ® Results: Of the 364 participants, 83.5% had high adherence to antiretroviral therapy while 16.5% had low adherence. Knowledge of antiretroviral therapy (OR 0.27, 95% CI: 0.14 -0.54) and antiretroviral therapy clinic site (OR 2.34, were statistically significantly associated with adherence to antiretroviral therapy in our study. for windows version 20.0 to ascertain the factors associated with adherence to antiretroviral therapy among the participants. Conclusion: Most of the participants were adherent to antiretroviral therapy. There is still need to give more information on human immunodeficiency virus and acquired immune deficiency syndrome and adherence to people living with human immunodeficiency virus and acquired immune deficiency syndrome especially before the initiation of antiretroviral therapy. Also, health care providers need to establish other possible barriers to antiretroviral therapy adherence so as to manage the patients better.
doi:10.21522/tijcr.2014.03.02.art010 fatcat:o43e3qgbkja5fnzjxae2kpelgu