PWE-023 Prognostic significance of circumferential resection margin status in oesophageal cancer—a systematic review and meta-analysis: Abstract PWE-023 Table 1

O Rotimi, D Greenwood, Y-K Tu
2012 Gut  
For patients receiving palliative oncology, we compared characteristics of completers and non-completers of chemotherapy using c 2 tests and multiple logistic regression models with correction for cluster sampling. For variables with missing data we imputed values using multiple imputation by chained equations. Results Of 16 264 patients participating in the NOGCA in England, 2313 received palliative chemotherapy treatment. Female patients or patients of older age were less likely to receive
more » ... ikely to receive treatment. Overall, only 39.7% completed their treatment. Factors associated with treatment completion were low performance status, high age and high level of deprivation. In our study, treatment completion was not related with site of cancer, pre-treatment stage, sex, comorbidities or histology. Conclusion Completion rates of palliative chemotherapy in patients with oesophago-gastric cancer are low. The low completion rates may reflect the complex medical decision making for this group of patients and the need to balance survival benefits, toxicity of treatment, patients' preferences and patients' quality of life. Patients unlikely to complete chemotherapy may be more appropriately managed on a palliative supportive care pathway with symptom control.
doi:10.1136/gutjnl-2012-302514d.23 fatcat:axc7ebaj3bgstkq56cew6rzlly