ASCENDING PARALYSIS

Alfred Gordon
1908 Journal of Nervous and Mental Disease  
THE PHILADELPHIA NEUROLOGICAL SOCIETY were moved-in all directions, but it was impossible to get the patient to make extreme movements of the eyeballs in any directions, nystagmus was not observed, ataxia was present in each upper limb, sensation to pin prick was preserved all over the body, the limbs were not weak, the patellar reflexes were lost even on reinforcement, the Achilles jerk was feeble on each side, the boy was unable to stand alone and would fall backwards if not supported,
more » ... t supported, hemiasynergia and diadococinesia could not be tested for because of the stupor, the corneal reflex was present, the Babinski reflex was very uncertain. The diagnosis of a lesion of the cerebellum was made and as the symp¬ toms indicated that the progress was gradual in development, a tumor was supposed to be present. Decompression was performed by Dr. Nassau and was followed rapidly by death on April 25, igo7. Only the cerebellum and a portion of the pons were obtained for examination. A cavity was found in the interior of the right dentate nucleus, and the left dentate nucleus did not appear to be normal. The small vessels of both cerebellar lobes near and in the dentate nuclei were much congested, and numerous small hemorrhages were found about them with some perivascular round cell infiltration. The vessels of the pons were congested and here also a few small hemorrhages and slight peri¬ vascular round cell infiltration were found. As the necropsy was neces¬ sarily so incomplete it was impossible to say whether any other intracranial lesion was present or not. This paper is founded upon the study of the spinal cord of a woman who died from carcinoma of the vertebra secondary to a primary breast lesion. There were symptoms of transverse lesion of the spinal cord almost two months before death, yet the microscopical study of the spinal cord demonstrated practically no secondary degeneration. Some of the prevailing theories as to parenchymatous regeneration in nerve tissue are mentioned and discussed, and the bearing of the absence of marked histo¬ logical change in the case cited upon laminectomy to fracture-dislocation of the spinal column with cord symptoms is considered. ASCENDING PARALYSIS
doi:10.1097/00005053-190807000-00014 fatcat:yr5t7gmo65cxvfirhicxn6sama