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Two experiments were conducted to compare theories of the functional organization of spatial working memory within the human prefrontal cortex. In Experiment I, memory set size for locations was parametrically varied, allowing for the assessment of BOLD signal across maintenance requirements. In the second experiment, manipulation of spatial information held in working memory was contrasted with simple maintenance of that information. Both experiments evoked significant activity in adoi:10.1006/nimg.2002.1161 pmid:12482077 fatcat:tq4pb4d43zfzhh73wxj3c7slgi