Comparative phytochemical and biological studies of lipoidal matter of Ipomoea tricolor (Cav.) and Ipomoea fistulosa (Mart. Ex Choisy ) growing in Egypt

Nabil Selim, Seham El Hawary, Hanan Aly, Azza Matlob, Magdy Elhenawy, Doaa Abd Elhady Deabes, Hanan Ebrahim
2021 Egyptian Journal of Chemistry  
Lipoidial profile of Ipomoea tricolor and Ipomoea fistulosa leaves were characterized by GC/MS led to the identification of 22 and 33 compounds represented (95.88 and 91.82 %), respectively, of I. tricolor and I. fistulosa unsaponifiable matter It is composed mainly of hydrocarbons and oxygenated compounds. The GC/MS of fatty acids methyl ester (FAME) led to the identification of 8 and 10 compounds for I. tricolor and I. fistulosa, respectively.Linolenic and palmatic acids were found as the
more » ... ominant fatty acids. On the other hand, the petroleum ether extract of I.tricolor was fractionated on column chromatography to yield major compounds; 5-phenyldecane and 4-phenyldecane, as well as, triterpenes including β-amyrin, lupeol and simiarenol,in addition to αamyrin, β-sitosterol, stigmasterol and αamyrin acetate which isolated for the first time from this species.The petroleum ether extracts of I. tricolorand I. fistulosa showed a significant increase in DPPHinhibition activity at 0.01 and 0.05 ug/ml, respectively. Furthermore, I.tricolor extract exhibited a significant increase in cholinesterase inhibition activity at concentration 20 ug/ml and a significant anti-inflammatory activity with IC50 117.4µg/ml. It can be concluded that pet.ether extracts of I.tricolor and I.fistulosa at different concentrations have significant antioxidant, anticholinesterase and antiinflammatory activities related to various bioactive identified compounds.
doi:10.21608/ejchem.2021.61245.3316 fatcat:xwuhacljbvhyze2h5bzscl37ey