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Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population
2021
Nature Communications
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AbstractAdipose tissue expansion, as seen in obesity, is often metabolically detrimental causing insulin resistance and the metabolic syndrome. However, white adipose tissue expansion at early ages is essential to establish a functional metabolism. To understand the differences between adolescent and adult adipose tissue expansion, we studied the cellular composition of the stromal vascular fraction of subcutaneous adipose tissue of two and eight weeks old mice using single cell RNA sequencing.
doi:10.1038/s41467-021-21826-9
pmid:33707431
fatcat:c72cknnnkze3hnts3fop5ijufu