Recently, green approaches for the synthesis of metal-based nanoparticles are gaining popularity due to their cost-effectiveness and environment friendly nature as compared to physical and chemical methods where different toxic chemicals are used which directly affect the environment. During synthesis of metal-based nanoparticles through green approach, various biological components like leaves, stems, roots, flowers etc. are used as stabilizing as well as reducing agents. According to WHO

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... t, metal-based nanoparticles have been used as an effective agent against different pathogens due to which they are also investigated for their biomedical applications. This review summarizes the overview of synthesis of metal-based nanoparticles (Ag, Au, Fe, Zn, Pd and Ni) and their antimicrobial activities. The novelty of this review is based on the comparative studies of different types of metal-based nanoparticles and their development as more effective antibacterial agents against multi-resistant gram-negative and gram-positive bacteria.