GASTRIC MUCOSAL CHANGES IN DUODENAL SWITCH OPERATION IN MANAGEMENT OF MORBID OBES ITY:PRE- AND POST-OPERATIVE COMPARISON
International Journal of Advanced Research
Atef mohamed abdel latif, mokhtar fareed abuelhoda, yaser ali elsayed, tamer youssef mohammed, ehab atef abdel -latif and amr esam el-ok da. Objecti ves: Duodenal switch has proved to be the most effective procedure in management of morbid obesity as it has long -term weight loss outcome and co-morbidity imp rovement.It is important to study the types of abnormal histopathologic pattern in the gastric mucosa in patients with duodenal switch operation and follow up of those changes 6 month after
... anges 6 month after the operation Methods: 25 morbid ly obese patients were included in this study. All patients were treated in the Endocrine Surgery Unit (ESU), Mansoura University Hospitals. ِAll patients did duodenal switch operation ( single anastomosis duodeno-ileal bypass with sleeve gastrectomy) and a biopsy from their gastric mucosa was taken at the time of the operation.Follow up of those patient was done six month after surgery regarding body weight, body mass index, weight loss and a biopsy was taken by upper gastrointestinal endoscope and compared with the previous data Result:The mean body weight six month after the operation was 116.2 ±15.2 kilo grams in comparison with 156.8 ±14.9 kilo grams at time of surgery with mean weight loss about 40.6 kilo grams and the mean body mass index six month after the operation is 40.7 ±4.4 in comparison with 55.0 ±4.7 at t ime of surgery with mean body mass index loss about 14. Normal gastric mucosa increased to 12 cases (48%) six month postoperative in comparison to seven cases (28%) at time of operation and Pathologic gastric mucosa decreased to 13 cases (52%) six month postoperative in co mparison to 18 cases (72%) at time of operation Conclusion: Open duodenal switch operation (Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy) for morb idly obese patients gives very good results in weight loss and control of diabetes mellitus type II and hypertension. As regards the epithelial changes after surgery it was noticed that there were imp rovement of the gastric mucosal pathology.