A survey of genetic simulation software for population and epidemiological studies

Youfang Liu, Georgios Athanasiadis, Michael E Weale
2008 Human Genomics  
A number of programs have been developed for simulating population genetic and genetic epidemiological data conforming to one of three main algorithmic approaches: 'forwards', 'backwards' and 'sideways'. This review aims to make the reader aware of the range of options currently available to them. While no one program emerges as the best choice in all circumstances, we nominate a set of those which currently appear most promising.
doi:10.1186/1479-7364-3-1-79 pmid:19129092 pmcid:PMC3525177 fatcat:3hn322lhajakjmrjwmergnaooq