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Antibiotic resistance is an extremely serious threat to the modern world. Since 2008, Gram-negative rods from the Enterobacteriaceae family gained the possibility of b-lactam degradation using NDM-1 carbapenemase, encoded by the blaNDM gene. It often occurs in the genome of Klebsiella pneumoniae and can occur on both bacterial chromosome and plasmids. This creates a very high risk due to the widespread occurrence of bacteria from this family both in the environment and in human microflora. Lackdoi:10.5603/mrj.a2019.0039 fatcat:zp742a5cbvhwtfrtv7zj63fb7y