Stereoselective synthesis of 17,18-epoxy derivative of EPA and stereoisomers of isoleukotoxin diol by ring opening of TMS-substituted epoxide with dimsyl sodium

Yutaro Nanba, Riku Shinohara, Masao Morita, Yuichi Kobayashi
2017 Organic and biomolecular chemistry  
The title three compounds were synthesized using the reaction of TMS-substituted epoxides with dimsyl sodium to produce 1-alkene-3,4-diol derivatives.
doi:10.1039/c7ob02291c pmid:28980682 fatcat:qdshqejgazgwnmcjjhpkc4fcsy