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BackgroundBipolar disorder onset peaks over early adulthood and confirmed family history is a robust risk factor. However, penetrance within families varies and most children of bipolar parents will not develop the illness. Individualized risk prediction would be helpful for identifying those young people most at risk and to inform targeted intervention. Using prospectively collected data from the Canadian Flourish High-Risk Offspring cohort study available in routine practice, we explored thedoi:10.21203/rs.3.rs-134834/v1 fatcat:637ge2whznaitna5vp3an7jp5e