Development and validation of a risk assessment scale for hepatic encephalopathy in cirrhotic patients [post]

2019 unpublished
This study aims to develop a risk assessment scale to assess and quantify risk of hepatic encephalopathy in cirrhotic patients. Methods: Data were derived from two Delphi rounds and a cross-sectional survey of 276 cirrhotic patients. The minimal consensus were a mean score 3.5 on a scale of 1 to 5, and a coe cient of variation 0.25. The reliability and validity of the scale were validated by a cross-sectional survey. Results: After two Delphi rounds and item analysis, a nal 23-item scale
more » ... two dimensions. The total Cronbach's αretest Cronbach's α, interrater Cronbach's α and split-half Cronbach's α were higher than 0.7, showing an acceptable reliability. The AUC was 0.792, and the sensitivity and speci city were 83.9% and 59.6%, respectively, indicating that the scale had a good predictive validity. Conclusion: This scale may be a promising tool for estimating and ranking risk of hepatic encephalopathy. Future research is necessary to apply it in hepatic encephalopathy.
doi:10.21203/rs.2.17653/v1 fatcat:zpzfs3qfrvd3lkn76dgq65nzji