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The avian pallium is organised into clusters of neurons and does not have layered structures such as those seen in the mammalian neocortex. The evolutionary relationship between sub-regions of avian pallium and layers of mammalian neocortex remains unclear. One hypothesis, based on the similarities in neural connections of the motor output neurons that project to sub-pallial targets, proposed the cell-type homology between brainstem projection neurons in neocortex layers 5 or 6 (L5/6) and thosedoi:10.1038/s41598-019-56960-4 pmid:31892722 pmcid:PMC6938507 fatcat:fwzyavmyejghdki5dq67lqavdq