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A Cross-Protection Experiment in Pigs Vaccinated with Haemophilus parasuis Serovars 2 and 5 Bacterins, and Evaluation of a Bivalent Vaccine under Laboratory and Field Conditions
Journal of Veterinary Medical Science
Cross-protection between Haemophilus parasuis serovars 2 and 5 was examined in pigs using a bacterin based vaccine, and subsequently the safety and efficacy of a bivalent vaccine were evaluated. Upon intratracheal challenge of a serovar 2 or 5 strain, pigs immunized with a monovalent vaccine were protected against challenge with a homologous serovar strain, but not with a heterologous serovar strain. Immunization with a bivalent vaccine containing both serovars 2 and 5 bacterins conferreddoi:10.1292/jvms.63.487 pmid:11411491 fatcat:pd4zdw4xi5bfbhujcki5fv2muy