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The role of the carotid sinus reflex in control of the blood flow in the left circumflex coronary artery was studied in nine open-chest dogs anesthetized with chloralose. Flow was measured with an electromagnetic flowmeter. The effects of bilateral common carotid occlusion were examined in a three-part experiment in each dog. (1) Under vagotomy (control) conditions, occlusion of both common carotid arteries resulted in tachycardia, increased blood pressure, and a decrease in coronary arterydoi:10.1161/01.res.23.2.223 pmid:5662575 fatcat:jicxm656zzfq3nqffezfblabnu