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Drug delivery systems based on sugar-macromolecule conjugates
2002
Current opinion in drug discovery & development
The specificity of carbohydrate-protein interactions can greatly outstrip that of many other ligand-binding systems; such is the enormous density of information that sugars can convey. In addition, macromolecules allow for the fine-tuning of active drug delivery through their great ability to undergo site-specific modification and their inherent physicochemical properties. Once combined, these two factors suggest that sugar-macromolecule conjugates, targeted using endogenous carbohydrate
pmid:11926134
fatcat:bcrft5kezfebfks6d3fqq5vuji