Perioperative Acute Kidney Injury

Charles Hobson, Rupam Ruchi, Azra Bihorac
2017 Critical care clinics  
Synopsis Acute kidney injury (AKI) is a common complication in the surgical patient and is associated with increases in mortality, an increased risk for chronic kidney disease (CKD) and hemodialysis after discharge, and increased cost. Better understanding of the risk factors that contribute to perioperative AKI has led to improved AKI prediction and will eventually lead to improved prevention of AKI, mitigation of injury when AKI occurs and enhanced recovery in patients who sustain AKI. The
more » ... elopment of advanced clinical prediction scores for AKI, new imaging techniques and novel biomarkers for early detection of AKI provides new tools toward these ends. Outcomes Postoperative AKI has been demonstrated to be common and associated with increased incidence of CKD, increased incidence of other postoperative complications, increased risk for short and long term mortality and much higher cost and resource utilization compared to patients with no postoperative AKI 2,3,12,24-33 . Two recent studies have demonstrated a continuous risk-adjusted association between postoperative increase in serum creatinine and Hobson et al.
doi:10.1016/j.ccc.2016.12.008 pmid:28284301 pmcid:PMC5617733 fatcat:66tacubqangh7jdl46ys3kju5a