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Lecture Notes in Computer Science
Tandem mass spectrometry has become central in proteomics projects. In particular, it is of prime importance to design sensitive and selective score functions to reliably identify peptides in databases. By using a huge collection of 140 000+ peptide MS/MS spectra, we systematically study the importance of many characteristics of a match (peptide sequence/spectrum) to include in a score function. Besides classical match characteristics, we investigate the value of new characteristics such asdoi:10.1007/978-3-540-39763-2_3 fatcat:ynkdam6usvhfdlxturwtqudlpq