Low Physical Function Predicts Either 2-Year Weight Loss or Weight Gain in Healthy Community-Dwelling Older Adults. The NuAge Longitudinal Study

D. St-Arnaud-McKenzie, H. Payette, K. Gray-Donald
2010 The journals of gerontology. Series A, Biological sciences and medical sciences  
Objectives. Weightchangeinolderadultsaffectsphysicalfunction(PF).However,datasuggestthat,conversely, PF maybeadeterminantofweightchange.OurobjectivewastoassesstheroleofbaselinePFasapredictorof2-yearweight loss(WL)andweightgain(WG)≥5%amonghealthywell-functioningcommunity-dwellingolderadults. Methods. TheNuAgecohort(67-84years)wasclassifiedintothreegroupsaccordingtothepercentweightchange overa2-yearfollow-up:weightstable(weightchange≤2%;n=629),WL≥5%(n=189),andWG≥5%(n=111).A
more » ... e PFwascomputed(sumofbiceps,quadriceps,andgripstrength,timedupandgo,chair stand,normalandmaximalgaitspeed,andbalanceperformancescores[individualtestscorerange=0-4];PFscore range=0-32).MultivariablelogisticregressionmodelsseparatelyassessedtherelationshipsbetweenbaselinePFand 2-yearWLandWG≥5%. Results. BaselinePFwasworseinboththeWL(p<.001)andtheWG(p=.001)groupscomparedwiththeweight stablegroup.Inmodelsadjustingforsex,age,bodymassindex,energyintake,depressivesymptoms,andothersignificantlyassociatedcovariates,each1-unitincreaseinstandarddeviationofPFwasassociatedwithdecreasedriskofeither 2-yearWL(oddsratio=0.79,95%CI=0.63-0.99,p=.043)orWG(oddsratio=0.74,95%CI=0.55-0.99,p=.041). Conclusions. LowbaselinePFwasanindependentcommonpredictorof2-year WLand WG≥5%inthehealthy well-functioningcommunity-dwellingelderlypopulation.WhetherPFisanearlycauseormarkerofweightchangein thispopulationremainstobedetermined.
doi:10.1093/gerona/glq150 pmid:20813794 fatcat:7ai4uuwtarf4rnjppq4awxno3e