Gastric Carcinoid in Three Bearded Dragons
フトアゴヒゲトカゲの胃原発カルチノイドの3例

Sho KADEKARU, Tetsuya SUZUKI, Yumi UNE
2010 Journal of the Japan Veterinary Medical Association  
Gastric carcinoids were observed in three adult female bearded dragons (Pogona vitticeps). Macroscopically, large and transmural tumors were seen in the stomach of all cases, and Case 3 had hepatic metastasis. Microscopically, in all cases, infiltrative tumor cells proliferated without capsulation and formed nests and ribbon-like rows of cells. Pseudorosette formation was observed in Case 2. Some tumor cells were poorly adhesive, having scant cytoplasm and small round pyknotic nuclei. The other
more » ... tumor cells had large, spindle shaped and bright nuclei. Immunohistochemically, the tumor cells were positive for chromogranin A and synaptophysin in all cases. Only Case 1 expressed cytokeratin. In electron microscopy, neuroendocrine granules averaging 220 nm in diameter were seen in the cytoplasm of the tumor cells in Case 3.
doi:10.12935/jvma.63.945 fatcat:mixgktdm65gm5dm74a7nxjrpoe