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MicroRNA-like viral small RNA from porcine reproductive and respiratory syndrome virus negatively regulates viral replication by targeting the viral nonstructural protein 2
2016
OncoTarget
Many viruses encode microRNAs (miRNAs) that are small non-coding singlestranded RNAs which play critical roles in virus-host interactions. Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most economically impactful viruses in the swine industry. The present study sought to determine whether PRRSV encodes miRNAs that could regulate PRRSV replication. Four viral small RNAs (vsRNAs) were mapped to the stem-loop structures in the ORF1a, ORF1b and GP2a regions of the PRRSV
doi:10.18632/oncotarget.12703
pmid:27769040
pmcid:PMC5347740
fatcat:gwuwmgclcffudgg2ndvyyfwbre