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Skull is the anatomic landmark for patient set up of head radiation therapy. Skull is generally segmented from CT images because CT provides better definition of skull than MR imaging. In the mean time, radiation therapy is planned on MR images for soft tissue information. This study utilized a knowledge-guided active model (KAM) method to segmented skull on MR images in order to enable radiation therapy planning with MR images as the primary planning dataset. KAM utilized age-specific skulldoi:10.1117/12.709801 dblp:conf/miip/ShanHJPYKMKR07 fatcat:fwhhqctuo5hptotd6gpgp2sqf4