Menopause is a gradual and natural transitional phase of adjustment between the active and inactive ovarian function and occupies several years of women's life and involves biological and psychological changes adjustments. This period is usually associated with unavoidable manifestation of ageing process in women. With menopause, women enter an estrogen deficient phase in their lives, which accelerates the ageing process. Though Rajonivritti as a disease condition is not described separately in

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... classical literature, Rajonivritti kala is mentioned by almost all classical texts. According to Sushrutha Samhita and other references too, 50 years is mentioned as the age of Rajonivritti, when the body is fully in the grip of senility. Sandhigata Vata is a most common condition which occur during this phase because of Dhatukshaya. Sandhigata Vata can be explained under the degenerative osteoarthritis according to contemporary science. Contemporary science suggests supplementation of estrogen as hormone replacement therapy in postmenopausal osteoarthritis. Sandhigata Vata in Rajonivritti has to be understood under Dhatukshayajanya Samprapti, which throws light into the utilization of Rasayana therapy, those specific to Asthidhatu Poshana in specific. Anupahata (unimpeded) dhatu Agni, Srotus and Vyana Vayu which is responsible for the sustenance of Sharira dhatu which is being fed by their poshaka dhatus, the derangement of which leads to hormonal disorders. This article aims at understanding the concept of Sandhigata Vata in Rajonivritti, considering Arthava Kshaya as the Nidana. Rasayana Chikitsa throws light into the scope of alternative therapy to hormone replacement therapy which works at the level of dhatu Agni, Srotus and Vyana Vayu. Application of phytoestrogens in such condition should also be considered as the supportive line of management. Keywords: Sandhigata Vata, Menopause, Estrogen, Rajonivritti, Rasayana, Osteoarthritis and Hormone Replacement Therapy (HRT)