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Stroke is one of the most common causes of death and long term disability throughout the world. It is not only induced by classic vascular risk factors like hypertension, cigarette smoking and diabetes mellitus, but also by genetic factors. The genetic etiology of ischemic stroke is polygenic. The candidate »stroke risk« genes may be conveniently divided into five groups, affecting (i) lipid metabolism, (ii) the renin-angiotensin system, (iii) haemostasis, (iv) nitric oxide production, and (v)doi:10.2298/jmh0504225s fatcat:m7mxo54uznaypm6tsgimbtbbey