Objectives: This investigation aimed to clarify the period prevalence (PP) and incidence rate (Irs) related to cancers of the urinary system in Isfahan province, Iran. Methods: Recorded data were obtained from the Isfahan Cancer Registry. The location of cancers was distinguished from the related established topography code (C64 -C68). Period prevalence (PP) and Irs was identified per 100000 persons. Results: There were 2117 patients with urinary system cancers. The mean age ± SD was 63.6 ±

more »

... years old, which in 62% ranged between 20 and 70 years. A value of 42.5 was calculated for PP that was associated with values of 66.4 for males and 17.9 for females (P < 0.001). The total PP corresponded to values of 33.2 for bladder, 8.1 for a kidney, 0.42 for renal pelvis, 0.36 for ureter and 0.38 for other unspecified related organs. Of these populations, the estimated living cases corresponded to 368 females and 1513 males. Conclusions: The PP for urinary system cancers in male population was 3.7 times higher than females. There was a 23.2% increase in the Irs over the study period. These findings highlighted the advantage of a focus on the risk of urinary system diseases, its evidence based pharmacotherapy and surgical management of such patients. In this process, providing clinical drug-management has potential importance in Iran.