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Noninvasive devices for fat reduction have become increasingly popular over the past decade. High-intensity focused ultrasound (HIFU), already in use for nearly half a century for the noninvasive treatment of tumors, has only recently been evaluated as a method for the selective ablation of adipose tissue. HIFU works by focusing high-intensity ultrasonic waves at the level of the subcutaneous adipose tissue, causing focal coagulative necrosis with contraction and thickening of adjacent collagendoi:10.2147/rrfu.s55831 fatcat:jpzy4ngbhrdnfpgctu2mkxgp3e