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Involvement of the FAK Network in Pathologies Related to Altered Mechanotransduction
International Journal of Molecular Sciences
Mechanotransduction is a physiological process in which external mechanical stimulations are perceived, interpreted, and translated by cells into biochemical signals. Mechanical stimulations exerted by extracellular matrix stiffness and cell–cell contacts are continuously applied to living cells, thus representing a key pivotal trigger for cell homeostasis, survival, and function, as well as an essential factor for proper organ development and metabolism. Indeed, a deregulation of thedoi:10.3390/ijms21249426 pmid:33322030 fatcat:tjudaz7zsjgzbdwxgy4vnewfyu