Spectrum of Clinico-Pathological Correlation of Abnormal Uterine Bleeding Cases in a Tertiary Care Hospital

Ismat Jahan, Ratu Rumana, Najnin Munni, Tasnuva Akter, Humayra ZU
2020 Surgical Research  
Citation: Jahan I, Rumana R, Munni N, et al. Spectrum of clinico-pathological correlation of Abnormal Uterine Bleeding cases in a tertiary care hospital. Surg Res. 2020; 2(1): 1-5. ABSTRACT Introduction: Abnormal Uterine Bleeding is a common problem encountered by women of all age groups, responsible for around 20-30% visits to out-patient department in reproductive age group. The International Federation of Gynaecology and Obstetrics working group on menstrual disorders has developed a
more » ... cation system-PALM COEIN for causes of AUB in non-pregnant women of reproductive age. Aim of the Study: To evaluate the correlation of histopathological findings with clinical & sonographic findings. Material & Methods: This was a cross sectional observational study, conducted in the Department of Obstetrics & Gynaecology, BIRDEM Hospital, Dhaka from 1st July 2015 to July 2017.One hundred patients of age range between 35-45 years who were clinically diagnosed as AUB & underwent total abdominal hysterectomy in BIRDEM Hospital. Results: A total of 100 cases were analyzed. Patients' age ranged from 35-45 years.The most common presenting symptom was heavy menstrual bleeding (62%). Most of the patients (60%) were initially treated medically before undergoing hysterectomy. In few patients (14%) hysterectomy was done as first treatment as the bleeding was severe. Endometrial proliferative pattern was the most common histopathological finding and was seen in 64% patients. Atypical endometrial hyperplasia in 5% patients, secretory endometrium in 15% and atrophic endometrium were seen in 4% patients each & Cystic hyperplasia in 7% patients. After exclusion of organic pathology (according to FIGO classification: PALM) through histopathological findings, diagnosis of AUB due to Nonstructural pathology like ovulatory dysfunction, Endometrial pathology was confirmed in 45% of cases. Conclusion: Histopathological examination of endometrium should be done generously in women presenting with AUB especially after the age of 40 years to rule out malignant pathology. Volume 2 | Issue 1 | 2 of 5 Surg Res, 2020 Keywords Abnormal uterine bleeding, Endometrial hyperplasia, Histopathology, Heavy menstrual bleeding.
doi:10.33425/2689-1093.1030 fatcat:s3r4tejxuvg25ibuxc4cvw4xuu