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Deoxycytidine Triphosphate Deaminase: Identification and Function in Salmonella typhimurium
Journal of Bacteriology
The biosynthesis of 2'-deoxyuridine monophosphate (dUMP) has been studied in a cytidineL and uracil-requiring mutant of Salmonella typhimurium (DP-55). The dUMP pool and the thymidine monophosphate (dTMP) pool of DP-55, grown in the presence of 3H-uracil and unlabeled cytidine, are found to have the same specific activities. However, only 30% of the dUMP and the dTMP is synthesized from a uridine nucleotide. Seventy per cent is derived directly from a cytosine compound. The identification anddoi:10.1128/jb.105.2.657-665.1971 fatcat:v6hxudir6napbiqpnb7vddo5h4