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Background: Inulin-type fructans have been used as prebiotics to alleviate glucose and lipid metabolism disorders. However, few studies evaluate the microbial mechanism of inulin in improving maternal metabolic status during pregnancy. Methods: We use high fat-sucrose diet-induced gestational diabetes mice as a model to study the effect of inulin-type fructans on the cecal microbiota by 16S rRNA gene amplicon sequencing. Results: The inulin-type fructans-supplemented diet improved glucose anddoi:10.21203/rs.3.rs-961635/v1 fatcat:bbixh46ogjdijletpmrhwmd4cy