Prognosis of acute kidney injury based on pRIFLE criteria among patients admitted to pediatric intensive care unit in Northern Iran; a single center study

Afshin Safaei-Asl, Mahsa Jilani, Abtin Heydarzadeh, Shohreh Maleknejad
2019 Journal of Renal Injury Prevention  
Acute kidney injury (AKI) is a frequent problem in pediatric intensive care units, while it is associated with significant mortality. Objectives: The aim of this study was to determine the prevalence and prognosis of AKI based on pRIFLE (pediatric risk, injury, failure, loss, end-stage renal disease) criteria among children admitted to a pediatric intensive care unit Patients and Methods: This research included 323 children from 1 month to 14 years old age, admitted to the pediatric intensive
more » ... diatric intensive care unit. The pRIFLE was determined in patients along with urinary output and creatinine level. The pediatric risk of mortality (PRISM) score was also assessed. Results: Mean PRISM III score was 34.66 ± 15.97 and 17.72 ± 6.06 respectively in children with and without AKI (P=0.001). It was found that variables of encephalopathy, PRISMIII score and gender were the only variables affecting the incidence of AKI. Conclusion: While pRIFLE criteria are appropriate and efficient criteria for early diagnosis of AKI, their role alone as prognostic factors of mortality require further studies.
doi:10.15171/jrip.2019.26 fatcat:zmr47r6nczaypad23xs7aculeu