Development of a Crystallization Step for Monoclonal Antibody Purification: Screening, Optimization and Aggregation Control

Yuguo Zang
An intact monoclonal antibody was purified through crystallization. The purity after one step purification was 95%, which was comparable to protein A chromatography. But this process still needs to be improved because of a low recovery rate of antibody.
doi:10.5445/ir/1000036609 fatcat:mq5gnpqovng7lampj2xl2o2zqi