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An unexpected re-arrangement of the antibiotic carbapenem core to new 1,4-diazepin-5-one scaffolds

Byron K. Peters, Rufaro Razuwika, Marivel Samipillai, Per I. Arvidsson, Hendrik G. Kruger, Thavendran Govender, Tricia Naicker
2018 RSC Advances  

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Herein we report a peculiar organocatalyzed domino-reaction on the carbapenem core structure.
doi:10.1039/c7ra12688c fatcat:fjsfcy52ffh7np46gzty4vot2e
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Byron K. Peters, Rufaro Razuwika, Marivel Samipillai, Per I. Arvidsson, Hendrik G. Kruger, Thavendran Govender, Tricia Naicker. "An unexpected re-arrangement of the antibiotic carbapenem core to new 1,4-diazepin-5-one scaffolds." RSC Advances 8.1 (2018) 190-193