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The epidemiology of nicotine dependence indicates how strongly addictive a drug it is that nearly half of those who ever smoked steadily for a month become highly nicotine dependent. It is a psychoactive substance that induces euphoria, reinforces its own use, and leads to nicotine withdrawal syndrome when it is absent. Subjects and Methods: Written informed consent was taken from all the cases and controls prior to the detailed assessment. The personal data was recorded in the sociodoi:10.21276/ajm.2019.2.2.11 fatcat:tahqljtg3bgkhfhozfqgmmr7fm