Chemical composition, circadian rhythm and antibacterial activity of essential oils of piper divaricatum: a new source of safrole

Queila P. S. Barbosa, Cláudio A. G. da Câmara, Clécio S. Ramos, Daniele C. O. Nascimento, José V. Lima-Filho, Elsie F. Guimarães
2012 Química Nova  
Recebido em 16/2/12; aceito em 11/5/12; publicado na web em 3/8/12 The essential oils from leaves, stems and fruits of Piper divaricatum were analyzed by GC-MS. The tissues showed high safrole content: leaves (98%), fruits (87%) and stems (83%), with yields of 2.0, 4.8 and 1.7%, respectively. This is a new alternative source of safrole, a compound widely used as a flavoring agent and insecticide. The leaf´s oil showed antibacterial activity against gramnegative bacteria while safrole was active
more » ... against Salmonella Typhimurium and Pseudomonas aeruginosa. In addition, the study of circadian rhythm of the safrole concentration in the essential oils of leaves showed a negligible variation of 92 to 98%.
doi:10.1590/s0100-40422012000900019 fatcat:rjiyarwa7rbsvknezawdusqpvu