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and aim: Thrombocytopenia is a common complication of chronic liver diseases and is due to various causes.The effect of thrombocytopenia on liver damage and the exact mechanisms that lead to thrombocytopenia in chronic liver disease and cirrhosis are still unclear. As Platelets Derived Growth Factor ß (PDGF-ß) is released from platelets (PLTs) upon activation. We tried to identify PLTs and PDGFR-ß in the liver to shed some light on the pathophysiology of thrombocytopenia and liver fibrosis in chronic hepatic C patients.doi:10.21608/smj.2018.40978 fatcat:ldylcr3k6fd5lk3qgjqwjodbgm