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A factor-image framework to quantification of brain receptor dynamic PET studies
2005
IEEE Transactions on Signal Processing
The positron emission tomography (PET) imaging technique enables the measurement of receptor distribution or neurotransmitter release in the living brain and the changes of the distribution with time and thus allows quantification of binding sites as well as the affinity of a radioligand. However, quantification of receptor binding studies obtained with PET is complicated by tissue heterogeneity in the sampling image elements (i.e., voxels, pixels). This effect is caused by a limited spatial
doi:10.1109/tsp.2005.853149
pmid:18769527
pmcid:PMC2185066
fatcat:j5btkf25p5fvlcw5nuv3i2tjja