We study the phase diagram of S=3/2 and S=2 bond-alternating spin chains numerically. In previous papers, the phase diagram of S=1 XXZ spin chain with bond-alternation was shown to reflect the hidden Z_2× Z_2 symmetry. But for the higher S Heisenberg spin chain, the successive dimerization transition occurs, and for anisotropic spin chains the phase structure will be more colorful than the S=1 case. Using recently developed methods, we show directly that the phase structure of the anisotropic spin chains relates to the Z_2× Z_2 symmetry.