Background: One of the technologies used to assist fertility is oocyte donation. Although there is sufficient information about medical aspects of oocyte donation; the psychological aspects of this treatment are not well-known. Self-concept investigates psychological aspects of people and therefore the aim of this study is aimed to compare self-concept of infertile women undergoing oocyte donation and fertile women. Method: In this descriptive-analytical study, 106 women selected using

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... ce sampling were divided into two groups of infertile women undergoing oocyte donation and fertile women. Data gathering tool in this study was two questionnaires including demographic information questionnaire and Rogers' standardized self-concept questionnaire. Data was analyzed using chi-square and t-test with the help of SPSS20 software. Results: The findings showed that self-concept of the majority of participants in both groups were weak. The score of infertile women undergoing oocyte donation was higher than fertile women and the difference between two groups was significant (P=0.045). Conclusion: Based on the results, it can be said that infertility and treatment using oocyte donation weakens one's self-concept. Therefore, it is necessary for authorities to make arrangements in order to evaluate mental health of infertile women undergoing oocyte donation.