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Discrete–continuous duality of protein structure space
2009
Current Opinion in Structural Biology
Recently, the nature of protein structure space has been widely discussed in the literature. The traditional discrete view of protein universe as a set of separate folds has been criticized in the light of growing evidence that almost any arrangement of secondary structures is possible and the whole protein space can be traversed through a path of similar structures. Here we argue that the discrete and continuous descriptions are not mutually exclusive, but complementary: the space is largely
doi:10.1016/j.sbi.2009.04.009
pmid:19482467
pmcid:PMC3688466
fatcat:hoerjrns4zhatpepsznyz2c5ym