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Method development and validation of visible spectroscopic method for the estimation of tramadol hydrochloride in pure and bulk dosage form
2015
Journal of Chemical and Pharmaceutical Research
unpublished
The present research work discusses the development of visible spectroscopic method for the estimation of Tramadol Hydrochloride. The optimum conditions for the analysis of the drug were established. The maximum wavelength (λ max) was found to be 749nm. The validation was performed as per ICH guidelines for linearity, accuracy, precision, LOD and LOQ. The method shows high sensitivity with linearity in the range of 10-50µg/ml and shows a linear relationship between the absorbance and
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