Design and synthesis of conformationally constraint Dyrk1A inhibitors by creating an intramolecular H-bond involving a benzothiazole core

Mohamed Salah, Mohammad Abdel-Halim, Matthias Engel
2018 MedChemComm  
We present the development of conformationally pre-organised Dyrk1A inhibitors based on the hydroxybenzothiazole urea scaffold.
doi:10.1039/c8md00142a pmid:30108993 fatcat:2slqwqmypnatfjmcklad3tgtde