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A case of lung cancer with chest wall invasion treated by preoperative thermo-chemo-radiotherapy revealed a histologically complete response after complete resection is reported. A 55-y ear-old male was diagnosed as primary lung cancer originating from the right upper lobe, cT3N0M0,stage IIB. The tumor invaded the right chest wall accompanied with obstructive pneumonia at its dorsal side and was rapidly growing. Thus, preoperative thermo-chemo-radiotherapy was performed. He was treated withdoi:10.3191/thermalmed.27.25 fatcat:7e5fszxidrdlll4yxjyed6npea